Searchable abstracts of presentations at key conferences in endocrinology

ea0090p151 | Pituitary and Neuroendocrinology | ECE2023

Novel provocation test with MDMA (“ecstasy’) reveals oxytocin deficiency as a new pituitary entity in patients with central diabetes insipidus – a randomized placebo-controlled trial

Atila Cihan , Holze Friederike , Murugesu Rakithan , Rommers Nikki , Hutter Nina , Varghese Nimmy , Clara Odilia Sailer , Eckert Anne , Heinrichs Markus , Liechti Matthias , Christ-Crain Mirjam

Introduction: Patients with arginine vasopressin deficiency (AVP-D), known as central diabetes insipidus (cDI), often report psychological symptoms such as heightened anxiety levels, difficulties describing emotions, and depressed mood despite adequate treatment with desmopressin. Given the anatomical proximity, disruptions of the hypothalamic-pituitary axis causing an AVP-D could also disturb the oxytocin (OXT) system. OXT regulates socio-emotional functioning, including fear...

ea0090ep314 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

The effect of olfactory odour stimulation on serum oxytocin levels and glucose metabolism: Data from the OLFAMET study

Matiashova Lolita , Hoogkamer Anouk , Komai Alexander , Kunz Chery , Popovic Milica , Spaar Yanick , Zehnder Elias , Minder Judith , Varghese Nimmy , Lemcke Antje Welge-Lussen , Eckert Anne , Timper Katharina

Background: Studies in rodents and non-human primates revealed beneficial effects of oxytocin on systemic metabolism, body weight and food intake. Several rodent studies demonstrated that olfactory stimulation with D-limonene, improves systemic glycemia, reduces food intake and body weight, while olfactory stimulation with the scent of lavender oil had opposite effects. The aim of this study was to investigate if systemic oxytocin levels are affected upon olfactory stimulation...